Ayaka MATSUMOTO松本 綾香

• March 2020 Graduated from Waseda University Honjo Senior High School
• April 2020 Entered Department of Life Science and Medical Bioscience, Faculty of Advanced Science and Engineering, Waseda Univ.
• March 2024 Graduated from Department of Life Science and Medical Bioscience, Faculty of Advanced Science and Engineering, Waseda Univ.
• April 2024 Entered Graduate School of Advanced Science and Engineering, Waseda Univ.

Crystal Optics Group

• Analysis of Racemization Reaction of Chiral Drug Thalidomide in Solid State

Thalidomide, Chirality, Crystals, Optical rotation, High-Performance Liquid Chromatography (HPLC), Circular dichroism

• Circular dichroism and optical activity of thalidomide in polar aprotic acetonitrile. Komei Okano, Moeri Iwata, Mizuki Kira, Ayaka Matsumoto, Takuya Nakanishi, Norio Shibata, Toru Asahi, Kenta Nakagawa. Chemistry Letters, 55(8), upag158, (2026)
• How Temperature Change Affects the Lattice Parameters, Molecular Conformation, and Reaction Cavity in Enantiomeric and Racemic Crystals of Thalidomide. Ayaka Matsumoto, Kenta Nakagawa, Takuya Nakanishi, Akiko Sekine, Sosuke Kojo, Mizuki Kira, Sota Sato, Norio Shibata, Toru Asahi. Journal of the American Chemical Society, 147(14), 11988-11997, (2025)
• Chiral Inversion of Thalidomide During Crystal Growth by Sublimation. Mizuki Kira, Yuta Shiga, Kenta Nakagawa, Ayaka Matsumoto, Keigo Tokita, Yukana Terasawa, Kun Zhang, Koichi Tsutao, Takuya Nakanishi, Satoshi Yoshida, Sota Sato, Norio Shibata, Toru Asahi. Crystal Growth & Design, 24(8), 3133-3139, (2024)

• 優秀ポスター賞 — 実験的に見出したサリドマイドの固体中でのキラル反転に対する計算化学による反応機構の検証 シンポジウム・モレキュラーキラリティー 2026 (2026)
• ポスター賞 — サリドマイドの固相状態におけるキラル反転機構の解析 Molecular Chirality2023 (2023)

• Poster実験的に見出したサリドマイドの固体中でのキラル反転に対する計算化学による反応機構の検証. 松本綾香, 中川鉄馬, 中西卓也, 国吉ニルソン, 吉良美月, 柴田哲男, 朝日透. Symposium on Molecular Chirality 2026 (MC2026) (東京理科大学（神楽坂キャンパス）) (2026)
• PosterUnraveling the Chiral Inversion of Thalidomide in Solid State through Computational Mechanistic Insights. 松本 綾香, 中川 鉄馬, 中西 卓也, 吉良 美月, 朝日 透, Nilson Kunioshi, Akiko Sekine, Norio Shibata. Chirality 2026 (2026)
• PosterRevelation of the difference in temperature dependence of the crystal and molecular structures between enantiomeric and racemic crystals of thalidomide with similar crystal structures. Ayaka Matsumoto, Kenta Nakagawa, Takuya Nakanishi, Akiko Sekine, Sosuke Kojo, Mizuki Kira, Sota Sato, Norio Shibata, Toru Asahi. 35th International Symposium on Chirality (Chirality 2025) (NY, USA) (2025)
• Oralサリドマイドのエナンチオマー結晶とラセミ結晶の結晶構造および分子間・分子内構造の温度依存性の研究. 松本綾香, 中川鉄馬, 中西卓也, 関根あき子, 古城綜佑, 吉良美月, 佐藤宗太, 柴田哲男, 朝日透. シンポジウム モレキュラー・キラリティー 2025 (名古屋大学 野依記念学術交流館) (2025)
• Oralサリドマイドのエナンチオマー結晶およびラセミ結晶における温度による構造変化の比較. 松本綾香, 中川鉄馬, 中西卓也, 関根あき子, 古城綜佑, 吉良美月, 佐藤宗太, 柴田哲男, 朝日透. 日本化学会 第105春季年会(2025) (関西大学) (2025)
• PosterX線構造解析によるサリドマイドのキラル結晶とラセミ結晶の結晶構造の温度依存性の比較. 松本綾香, 中川鉄馬, 中西卓也, 関根あき子, 古城綜佑, 吉良美月, 佐藤宗太, 柴田哲男, 朝日透. 分子研研究会「キラリティが関連する動的現象」 (岡崎) (2025)
• PosterX線単結晶構造解析によるサリドマイドの結晶構造の温度依存性の研究. 松本綾香, 中川鉄馬, 中西卓也, 関根あき子, 吉良美月, 佐藤宗太, 柴田哲男, 朝日透. 第32回有機結晶シンポジウム (東京工業大学・大岡山キャンパス) (2024)
• PosterDetermination of temperature dependence of crystal structure in thalidomide using X-ray single crystal structure analysis. Ayaka Matsumoto, Kenta Nakagawa, Takuya Nakanishi, Mizuki Kira, Yukana Terasawa, Norio Shibata, Toru Asahi. 2024国際キラリティー連合会議 (Kyoto, Japan) (2024)
• PosterComparison of Chiral Inversions in Thalidomide between Solution and Solid States. Ayaka Matsumoto, Mizuki Kira, Yuta Shiga, Kenta Nakagawa, Takuya Nakanishi, Yukana Terasawa, Norio Shibata, Toru Asahi. MRM2023/IUMRS-ICA2023 (Kyoto in Japan) (2023)
• Posterサリドマイドの溶液状態及び固体状態におけるラセミ化の比較. 松本綾香, 吉良美月, 志賀勇太, 中川鉄馬, 中西卓也, 寺澤有果菜, 柴田哲男, 朝日透. 第31回有機結晶シンポジウム (銀杏会館（大阪大学・吹田キャンパス）) (2023)
• Posterサリドマイドの固相状態におけるラセミ化反応の検証. 松本綾香, 吉良美月, 志賀勇太, 中川鉄馬, 中西卓也, 寺澤有果菜, 柴田哲男, 朝日透. 令和5年度日本結晶学会年会 (宇部市文化会館・山口大学常盤キャンパス) (2023)
• PosterInvestigation of Reaction Rate of Chiral Inversion of Thalidomide in Solid State. Ayaka Matsumoto, Mizuki Kira, Yuta Shiga, Kenta Nakagawa, Takuya Nakanishi, Yukana Terasawa, Norio Shibata, Toru Asahi. 19th International Conference on Chiroptical Spectroscopy (CD2023) (Hiroshima in Japan) (2023)
• PosterAnalysis of Racemization Reaction of Thalidomide in Solid State. Ayaka Matsumoto, Mizuki Kira, Yuta Shiga, Kenta Nakagawa, Takuya Nakanishi, Yukana Terasawa, Norio Shibata, Toru Asahi. Chirality 2023 (Rome) (2023)
• Posterサリドマイドの固相状態におけるキラル反転機構の解析. 松本 綾香, 吉良 美月, 志賀 勇太, 中川 鉄馬, 中西 卓也, 寺澤 有果菜, 柴田 哲男, 朝 日 透. Molecular Chirality2023（北海道大学 フード&メディカルイノベーション国際拠点 （FMI）） (2023)

• [1] Grant-in-Aid for JSPS Fellows (DC1), Japan Society for the Promotion of Science (FY2026–2028)

• ◆Award history
• [3] ProLab Holdings “2nd Business Idea Contest for Students” Aesthetic Pro Lab Award (2023)
• [2] JFTD Hana Cupid "Business Idea Pitch Contest" Hana Cupid Award (2020)
• [1] Waseda University Honjo Senior High School Award (2020)
• ◆Scholarship
• [1] Keyence Foundation “Ganbare! Japanese University Student Support Benefit” (2023)
• ◆Keynote & Speaking Engagements
• [4] Guest Lecturer, Waseda University Honjo Senior High School, Extracurricular Lecture Series “This Is Science! Vol. 5” (2026)
• Lecture Title: “Welcome to the World of Chirality!”
• [3] The 196th BPIA Research Meeting “Eye-Opening!” Presentation (2025)
• Lecture Title: “Entrepreneurship as Seen Through Student Challenges – A Youth Perspective Connecting Learning and Practice”
• [2] Spoke at the Institute of Management Studies "HR Department Leaders Forum" (2025)
• [1] Japan Society for Social Innovation 4th Annual Conference Subcommittee 3: Youth Talks about Social Innovation Planning Team/Youth Members (2022)
• ◆Program Completion
• [2] Certification of Completion, Institute for Business and Finance, Waseda University; Rady School of Management, University of California, San Diego (2025)
• [1] Epistimi Leading Yourself and Others US-Japan Foundation Workshop in Tokyo, Japan (2024)